Things that are difficult to say when you're drunk . .
Innovative
Preliminary
Proliferation
Cinnamon

Things that are VERY difficult to say when you're drunk...
Specificity
British Constitution
Passive-aggressive disorder
Transubstantiate

Things that are DOWNRIGHT IMPOSSIBLE to say when you're drunk...
Thanks, but I don't want to sleep with you.
Nope, no more booze for me.
Sorry, but you're not really my type.
No kebab for me, thank you.
Good evening officer, isn't it lovely out tonight?
I'm not interested in fighting you.
Oh, I just couldn't - no one wants to hear me sing.
Thank you, but I wont make any attempt to dance, I have zero co-ordination.
Where is the nearest toilet? I refuse to vomit in the street